2026
A respiratory signature of disease progression in the Pompe rat.
Mickle AR, Rana S, Benevides ES, Byrne BJ, Fuller DD, Dale EA.
J Neurophysiol. 2026 Feb 1;135(2):443-456. doi: 10.1152/jn.00305.2025.
Motor Neuron Size-Dependent Differences in mRNA Expression of Tropomyosin-Related Kinase Receptor B in Adult Rats
Martinez RC*, Rana S*, Gransee HM, Sieck GC, Mantilla CB.
J Neurochem. 2026 Feb;170(2):e70381. doi: 10.1111/jnc.70381.
2025
Acute Administration of Ampakine CX1739 after Cervical Spinal Cord Injury.
Fusco AF, Rana S, Macintyre MM, Gonzalez IA, Ribas RA, Sun RC, Fuller DD.J Neurotrauma. 2025 Oct 6. doi: 10.1177/08977151251382939.
Serum evaluation of NFL correlates with histological identification of degenerating axons
Fusco AF, Rana S, Rayaprolu S, MacIntyre MM, Jorgensen M, Shaw G, Fuller DD.Exp Neurol. 2025 Oct;392:115360. doi: 10.1016/j.expneurol.2025.115360.
Neonatal systemic gene therapy restores cardiorespiratory function in a rat model of Pompe disease
Fuller DD, Rana S, Thakre PP, Benevides ES, Pope MK, Todd AG, Jensen VN, Vaught L, Cloutier DA, Ribas RA, Larson RC, Gentry MS, Sun RC, Chandran V, Corti M, Falk DJ, Byrne BJ.Mol Ther. 2025 Sep 3;33(9):4276-4289. doi: 10.1016/j.ymthe.2025.06.022.
Chemogenetic stimulation of phrenic motor output and diaphragm activity.
Benevides ES, Thakre PP, Rana S, Sunshine MD, Jensen VN, Oweiss K, Fuller DD.Elife. 2025 Jun 2;13:RP97846. doi: 10.7554/eLife.97846.PMID: 40454577
Lessons Learned and Recommendations from a SCOPE Spinal Cord Injury Neurorestorative Clinical Trials Update
Kondiles BR, Rana S, Weiner D, Blesch A, St John J, Haag-Molkenteller C, Freund P, Guest J, Mikol DD, Harkema S, Trumbower RD, Fehlings MG, Weidner N, Hogge GS, Field-Fote EC, Baptista MAS, Curt A, Hsieh J, Jones L.Neurotrauma Rep. 2025 Mar 5;6(1):210-231. doi: 10.1089/neur.2024.0163. eCollection 2025.PMID: 40309157
Chemogenetic activation of the diaphragm after spinal cord injury in rats
Benevides ES, Rana S, Fuller DD.Respir Physiol Neurobiol. 2025 Aug-Sep;336:104421. doi: 10.1016/j.resp.2025.104421. Epub 2025 Mar 26.PMID: 40154905
Amplification of the therapeutic potential of AMPA receptor potentiators from the nootropic era to today
Radin DP, Lippa A, Rana S, Fuller DD, Smith JL, Cerne R, Witkin JM.Pharmacol Biochem Behav. 2025 Mar;248:173967. doi: 10.1016/j.pbb.2025.173967. Epub 2025 Jan 31.PMID: 39894310 Review.
Immunohistochemical labeling of ongoing axonal degeneration 10 days following cervical contusion spinal cord injury in the rat
Fusco AF, Rana S, Jorgensen M, Bindi VE, Sunshine MD, Shaw G, Fuller DD.Spinal Cord. 2025 Feb;63(2):86-94. doi: 10.1038/s41393-024-01053-x. Epub 2025 Jan 3.PMID: 39753895
Pharmacological modulation of respiratory control: Ampakines as a therapeutic strategy
Rana S, Fusco AF, Witkin JM, Radin DP, Cerne R, Lippa A, Fuller DD.Pharmacol Ther. 2025 Jan;265:108744. doi: 10.1016/j.pharmthera.2024.108744. PMID: 39521442
2024
AMPA receptors play an important role in the biological consequences of spinal cord injury: Implications for AMPA receptor modulators for therapeutic benefit
Witkin JM, Radin DP, Rana S, Fuller DD, Fusco AF, Demers JC, Pradeep Thakre P, Smith JL, Lippa A, Cerne R.Biochem Pharmacol. 2024 Oct;228:116302. doi: 10.1016/j.bcp.2024.116302. Epub 2024 May 18.PMID: 38763261
Ampakines increase diaphragm activation following mid-cervical contusion injury in rats
Rana S, Thakre PP, Fuller DD.Exp Neurol. 2024 Jun;376:114769. doi: 10.1016/j.expneurol.2024.114769. Epub 2024 Apr 4.PMID: 38582278
Acute ampakines increase voiding function and coordination in a rat model of SCI
Rana S, Alom F, Martinez RC, Fuller DD, Mickle AD.Elife. 2024 Mar 7;12:RP89767. doi: 10.7554/eLife.89767.PMID: 38451184
2023
Uman-type neurofilament light antibodies are effective reagents for the imaging of neurodegeneration
Shaw G, Madorsky I, Li Y, Wang Y, Jorgensen M, Rana S, Fuller DD.Brain Commun. 2023 Mar 16;5(2):fcad067. doi: 10.1093/braincomms/fcad067. eCollection 2023.PMID: 37091583
Size-dependent differences in mitochondrial volume density in phrenic motor neurons
Fogarty MJ, Rana S, Mantilla CB, Sieck GC.J Appl Physiol (1985). 2023 Jun 1;134(6):1332-1340. doi: 10.1152/japplphysiol.00021.2023. Epub 2023 Apr 6.PMID: 37022966
Optogenetic activation of the tongue in spontaneously breathing mice
Singer ML, Benevides ES, Rana S, Sunshine MD, Martinez RC, Barral BE, Byrne BJ, Fuller DD.Respir Physiol Neurobiol. 2023 Mar;309:103998. doi: 10.1016/j.resp.2022.103998. Epub 2022 Nov 22.PMID: 36423822
Targeting drug or gene delivery to the phrenic motoneuron pool
Thakre PP, Rana S, Benevides ES, Fuller DD.J Neurophysiol. 2023 Jan 1;129(1):144-158. doi: 10.1152/jn.00432.2022. Epub 2022 Nov 23.PMID: 36416447
Breathing patterns and CO2 production in adult spiny mice (Acomys cahirinus)
Rana S, Sunshine MD, Gaire J, Simmons CS, Fuller DD.Respir Physiol Neurobiol. 2023 Jan;307:103975. doi: 10.1016/j.resp.2022.103975. Epub 2022 Oct 4.PMID: 36206972
2022
Chemogenetic activation of hypoglossal motoneurons in a mouse model of Pompe disease
Singer ML, Rana S, Benevides ES, Barral BE, Byrne BJ, Fuller DD.J Neurophysiol. 2022 Nov 1;128(5):1133-1142. doi: 10.1152/jn.00026.2022. Epub 2022 Aug 17.PMID: 35976060
The phrenic neuromuscular system
Fuller DD, Rana S, Smuder AJ, Dale EA.Handb Clin Neurol. 2022;188:393-408. doi: 10.1016/B978-0-323-91534-2.00012-6.PMID: 35965035
Optogenetic activation of the diaphragm
Benevides ES, Sunshine MD, Rana S, Fuller DD.Sci Rep. 2022 Apr 20;12(1):6503. doi: 10.1038/s41598-022-10240-w.PMID: 35444167
Cervical spinal hemisection alters phrenic motor neuron glutamatergic mRNA receptor expression
Rana S, Zhan WZ, Sieck GC, Mantilla CB.Exp Neurol. 2022 Jul;353:114030. doi: 10.1016/j.expneurol.2022.114030. Epub 2022 Mar 2.PMID: 35247372
2021
Ampakines Stimulate Diaphragm Activity after Spinal Cord Injury
Rana S, Sunshine MD, Greer JJ, Fuller DD.J Neurotrauma. 2021 Dec;38(24):3467-3482. doi: 10.1089/neu.2021.0301.PMID: 34806433
Case Studies in Neuroscience: Neuropathology and diaphragm dysfunction in ventilatory failure from late-onset Pompe disease
Fuller DD, Trejo-Lopez JA, Yachnis AT, Sunshine MD, Rana S, Bindi VE, Byrne BJ, Smith BK.J Neurophysiol. 2021 Aug 1;126(2):351-360. doi: 10.1152/jn.00190.2021. Epub 2021 Jun 30.PMID: 34191636
Gene delivery to the hypoglossal motor system: preclinical studies and translational potential
Doyle BM, Singer ML, Fleury-Curado T, Rana S, Benevides ES, Byrne BJ, Polotsky VY, Fuller DD.Gene Ther. 2021 Aug;28(7-8):402-412. doi: 10.1038/s41434-021-00225-1. Epub 2021 Feb 11.PMID: 33574581
Quantifying mitochondrial volume density in phrenic motor neurons
Fogarty MJ, Rana S, Mantilla CB, Sieck GC.J Neurosci Methods. 2021 Apr 1;353:109093. doi: 10.1016/j.jneumeth.2021.109093. Epub 2021 Feb 4.PMID: 33549636
Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin
Gaire J, Varholick JA, Rana S, Sunshine MD, Doré S, Barbazuk WB, Fuller DD, Maden M, Simmons CS.NPJ Regen Med. 2021 Jan 4;6(1):1. doi: 10.1038/s41536-020-00111-1.PMID: 33397999
Age-related impairment of autophagy in cervical motor neurons
Pareja-Cajiao M, Gransee HM, Stowe JM, Rana S, Sieck GC, Mantilla CB.Exp Gerontol. 2021 Feb;144:111193. doi: 10.1016/j.exger.2020.111193. Epub 2020 Dec 5.PMID: 33290859
2020
Disproportionate loss of excitatory inputs to smaller phrenic motor neurons following cervical spinal hemisection
Rana S, Zhan WZ, Mantilla CB, Sieck GC.J Physiol. 2020 Oct;598(20):4693-4711. doi: 10.1113/JP280130. Epub 2020 Aug 19.PMID: 32735344
Heterogeneous glutamatergic receptor mRNA expression across phrenic motor neurons in rats
Rana S, Sieck GC, Mantilla CB.J Neurochem. 2020 Jun;153(5):586-598. doi: 10.1111/jnc.14881. Epub 2019 Oct 17.PMID: 31563147
2019
Glutamatergic input varies with phrenic motor neuron size
Rana S, Mantilla CB, Sieck GC.J Neurophysiol. 2019 Oct 1;122(4):1518-1529. doi: 10.1152/jn.00430.2019. Epub 2019 Aug 7.PMID: 31389739
Diaphragm muscle function following midcervical contusion injury in rats
Khurram OU, Fogarty MJ, Rana S, Vang P, Sieck GC, Mantilla CB.J Appl Physiol (1985). 2019 Jan 1;126(1):221-230. doi: 10.1152/japplphysiol.00481.2018. Epub 2018 Sep 20.PMID: 30236045
2017
Diaphragm electromyographic activity following unilateral midcervical contusion injury in rats
Rana S, Sieck GC, Mantilla CB.J Neurophysiol. 2017 Feb 1;117(2):545-555. doi: 10.1152/jn.00727.2016. Epub 2016 Nov 9.PMID: 27832610
