About Us
Our Journey in Neuroscience Research
Our Mission
At the Rana Lab in the Department of Neuroscience, we are committed to studying neural control of breathing in disease and injury. Our focus is on developing innovative solutions to understand and address respiratory challenges using cutting-edge research and technology. With a dedicated team, we strive to advance our understanding of the neural mechanisms underlying breathing control.
Our Methodology
Our lab is currently developing a suite of therapeutic approaches that include both pharmacological and neuromodulation techniques to improve respiratory outcomes following spinal cord injuries. We employ a highly interdisciplinary approach, incorporating in vivo neurophysiological recordings in awake and anesthetized animals, non-invasive spinal stimulation techniques, pharmacological interventions, genetic gain and loss-of-function strategies, and targeted rehabilitation protocols. These diverse methodologies enable a comprehensive understanding of respiratory neural circuits and the development of innovative therapeutic strategies for improving breathing in spinal cord injury models.
Our Research Directions
Neural Control of Breathing
Investigating fundamental mechanisms of how the brain, the spinal cord and the muscle work together to help us breathe.
Impaired respiratory function
Exploring the impact of neurological conditions on breathing function. In particular, we are studying the impact of spinal injuries on the full complement of respiratory function.
Recovery and Rehabilitation
Advancing research on motor (breathing, bladder, upper extremity) and sensory (pain) rehabilitation and recovery following neurologic insults, aiming to improve the quality of life for individuals.
Pathophysiology of neural injuries
Pioneering the development of novel technologies to assess and modulate the pathophysiology of spinal injuries, offering new possibilities for neuroprotective and therapeutic advancements in the field of neurotrauma.
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